Apoptosis Reagents and Kits
Abcam Human CXCR4 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human CXCR4 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human CXCR4.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human DAXX knockout HeLa cell lysate.
Human DAXX knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human IL6ST (CD130/gp130) knockout A549 cell lysate.
Human IL6ST (CD130/gp130) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human DROSHA knockout HEK-293T cell lysate.
Human DROSHA knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human LGALS1 (Galectin 1) knockout HEK-293T cell lysate.
Human LGALS1 (Galectin 1) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human HSPA8 (Hsc70) knockout HeLa cell lysate.
Human HSPA8 (Hsc70) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human IRF3 knockout A549 cell lysate.
Human IRF3 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Tau (phospho T217) Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Tau (phospho T217) Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Tau (phospho T217).
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Caspase-1 Rabbit mAb
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits large and small that dimerize to form the active enzyme This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1 a cytokine involved in the processes such as inflammation septic shock and wound healing This gene has been shown to induce cell apoptosis and may function in various developmental stages Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease Alternative splicing results in transcript variants encoding distinct isoforms
Abcam Human TNFRSF10B (DR5) knockout HeLa cell lysate.
Human TNFRSF10B (DR5) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CAPN2 (Calpain 2) knockout HEK-293T cell lysate.
Human CAPN2 (Calpain 2) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen m-3M3FBS
Chemical. CAS 200933-14-8. Formula C16H16F3NO2S. MW 343.4. m-3M3FBS is a cell permeable and specific activator of phospholipase C PLC that has been shown to stimulate the PLC-mediated intracellular Ca2 release, inositol phosphates production and superoxide generation in various cell types. It activates all PLC isotypes beta2, beta3, gamma1, gamma2 and delta1 in vitro, but not heterotrimeric G proteins, PI 3-kinase or PLD. m-3M3FBS also affects calcium homeostasis independently of PLC activation. m-3M3FBS induces apoptosis in tumor cells through caspase activation, down-regulation of XIAP and intracellular calcium signaling. m-3M3FBS has been shown in vitro to trigger mitochondrial damage and activate NLRP10 a bona fide inflammasome binding to Asc and Caspase-1 in keratinocytes. NLRP10 acts also as inflammasome in intestine epithelial cells and protects against autoinflammation in the gut.
Abcam Human TNFRSF1A (TNF Receptor I) knockout HeLa cell lysate.
Human TNFRSF1A (TNF Receptor I) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Annexin V-APC/DAPI Apoptosis Kit 20tests
Annexin V-APC/DAPI Apoptosis Kit allow discrimination between cells at various stages of apoptosis and cell death Annexin V is a calcium-dependent phospholipid-binding protein which specifically binds to phosphatidylserine (PS) Under normal conditions PS is located on the inner surface of the cell membrane lipid bilayer but during early apoptosis PS translocates from the inner leaflet to the outer leaflet of the plasma membrane becoming exposed to the extracellular environment By using Annexin V-APC labeling apoptotic cells can be detected easily through flow cytometry or fluorescence microscopy within 15-30 minutes Additionally this kit includes the nuclear stain DAPI which specifically binds to double-stranded DNA to emit blue fluorescence Normally DAPI cannot penetrate intact cell membranes In late apoptotic and dead cells DAPI can cross the compromised membrane to stain the nucleus
Abcam Human IRAK4 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human IRAK4 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human IRAK4.
The product is subject to the following: Abcam Restricted Use Statement